[Prevention of deteriorations of blood biochemical indices in experimental stress in rats].

Results of the research of the impact of extract from the byproducts of guelder-rose, containing a complexflavonoides (65% of dry weight), in the conditions of experimental a stress (vertical fixing of rats by a dorsal cervicalfold for 22 o'clock) are presented. The impact of a stress was shown to be followed by the gain in mass of adrenal glands by 42%. In blood serum there were noted marked hypertriglyceridemia, hypercholesterolemia, increased superoxide dismutase activity, decline in the number of reduced glutathione and anti-radical activity, the gain in lisofractions of phospholipids, decrease of phosphatidylcholine, phosphatidylethanolamine, cholesterol esters. Administration of the extract from the byproducts of guelder rose crushing promoted the normalization of indices of mass of adrenal glands and lipid metabolism in blood serum, was more effective, than a reference stress protector "Extract eleuterokokka®". The introduction of eleuterococcus was followed by the persistent both elevated level of cholesterol, free fatty acids, lisofraction of phospholipidsand low level offatty acids esters, cholesterol esters and a diphosphatidilglicerin. Byproducts of guelder-rose were shown to represent a perspective view of raw materials for the producing of stress protective preparations.

[Peculiarities of adaptation of servicemen service].

Review of issues about the adaptation of servicemen in the process of military service is presented. Characteristics of military service, conditions and levels of official-military activity, peculiarities of adaptation, factors providing progression of psychosomatic diseases and dysaptation, concept "occupational health" are considered.

[Health improvement in children with ecological dysadaptation syndrome treated at a health resort].

A method for the spa-and-resort treatment of children residing under conditions of ecological discomfort has been developed. It includes drinking weakly mineralized hydrocarbonate-sodium sulfate-sodium-calcium carbon dioxide water from the Slavyanovsk spring and slightly carbonaceous mineral baths in combination with magnetotherapy. This treatment is shown to improve characteristics of somatic and neurological status, activate metabolic processes, accelerate lymphokinesis and blood circulation. Collectively, these effects enhanced the children's health potential.

[Application of balneotherapeutic factors in the system of rehabilitative treatment of children with environmental dysadaptation syndrome].

Combined balneotherapy including intake and external application of Zheleznovodsk-type mineral water was given to 60 children at the age from 7 to 14 years presenting with environmental dysadaptation syndrome. This treatment ensured favourable dynamics of clinical signs of asthenovegetative, dyspeptic, and pain syndromes. Moreover, it exerted beneficial influence on the mechanisms of vegetative regulation, improved the psychoemotional status of the patients and functional capacity of their immune system.

[Hypobaric interval hypoxia as a tool for improving tolerance of harmful occupational factors].

The method of hypobaric interval hypoxia (HIH) has been developed and approved for application in aerospace, military, prophylactic and rehabilitative medicine. A course of H1H included 10 one-hour daily sessions of hypobaria and interval hypoxia simulating ascent to an altitude from 3 to 5 km a.s.l. Each session comprised a 7 minute exposure to hypoxia (breathing rarified air) alternating with a 3 minute exposure to hyperoxia (breathing oxygen) without a change of the altitude simulated in the low-pressure chamber. The first session included ascent to 3 km, in each of the following sessions (from 2nd to 4th) the altitude was successively increased by 500 m and reached 5 km in sessions 5-10. HIH was shown to be highly efficacious in improving the functional state of the organism and its resistance to unfavourable environmental conditions; also it can be used to correct changes of these parameters.

Estrés en recién nacidos internados en unidad de cuidados intensivos (UCIN): propuestas para minimizar sus efectos / Stress in newborn hospitalized in intensive care units (ICU): proposals to minimize its effects

Se presenta un trabajo de actualización y revisión bibliográfica sobre el tema de estrés en los recién nacidos internados en las Unidades de Cuidados Intensivos Neonatales. Se define este estrés y se lo diferencia del distrés o estrés crónico, explicando sus componentes fisio-psicopatológicos y sus etapas. Se clasifican sus desencadenantes o estresores. Se caracteriza el estrés en los RN y sus padres, y cuáles son sus indicadores. Se plantea las propuestas y recursos desde el equipo de salud y cómo lo enfrentan y superan el RN y su familia. ¿Qué es ôresilienciaõ? Se hace una revisión de las resoluciones según diferentes autores y se relata la modalidad de trabajo y la experiencia en la UCIN en el Hospital ôRamón Sardáõ.

Estrés en recién nacidos internados en unidad de cuidados intensivos (UCIN): propuestas para minimizar sus efectos / Stress in newborn hospitalized in intensive care units (ICU): proposals to minimize its effects

Se presenta un trabajo de actualización y revisión bibliográfica sobre el tema de estrés en los recién nacidos internados en las Unidades de Cuidados Intensivos Neonatales. Se define este estrés y se lo diferencia del distrés o estrés crónico, explicando sus componentes fisio-psicopatológicos y sus etapas. Se clasifican sus desencadenantes o estresores. Se caracteriza el estrés en los RN y sus padres, y cuáles son sus indicadores. Se plantea las propuestas y recursos desde el equipo de salud y cómo lo enfrentan y superan el RN y su familia. ¿Qué es ¶resiliencia÷? Se hace una revisión de las resoluciones según diferentes autores y se relata la modalidad de trabajo y la experiencia en la UCIN en el Hospital ¶Ramón Sardá÷. (AU)

[The characteristics of the development of an adaptation syndrome in severe gestosis]. / Osobennosti formirovaniia adaptatsionnogo sindroma pri tiazhelom gestoze.

Basic metabolic pathways were studied of formation of the adaptive syndrome in the organism of patients with grave gestoses: glycolysis, gluconeogenesis, and pentosephosphate pathway of production of nicotinamide coenzymes. It has been found out that a stressful character of reconstruction of metabolic homeostasis tends to change the processes of glycolysis and gluconeogenesis that had come to be formed by evolution. This warrants further study, its purpose being a specific correction of intracellular metabolism and prevention of complications. Ozonohemo- and antioxidant therapy in a complex of intensive treatment measures for patients with severe gestoses make for stimulation of pentosephosphate pathway and glycolysis.

[The characteristics of disorders of general adaptation reactions in people who suffered as a consequence of the accident at the Chernobyl Atomic Electric Power Station and their correction by means of balneo- and phytotherapy]. / Osoblyvosti porushen' zahal'nykh adaptatsiinykh reaktsii u osib, iaki postrazhdaly vnaslidok avariï na ChAES, ta ïkh korektsiia zasobamy bal'neo- i fitoterapiï.

Pathological general adaptive reactions of the body (GARs) were found out to occur on 33.8 +/- 5.0 of patients with chronic pathologies of the urinary and digestive organs, arriving at the Truskavets health resort from the areas contaminated with radionuclides, compared with 7.0 +/- 2.1% of diseased controls. Complex spa treatment during a period of two weeks involving ingestion of the mineral water "naftusia" has a beneficial effect on pathologic and premorbid GARs though not effectively so. Adaptogenic effect of balneotherapy is potentiated by use of balsam "Kryms'kyi" but not a home preparation ginseng.

Regulation of protein metabolism during stress.

Stress induces a hypermetabolic state of increased urinary nitrogen loss and increased metabolic rate. The principal reason for such a response is the mobilization of amino acids and the production of glucose to provide energy for the cells involved in the host immune response and wound repair. The endocrine hormones, eg, cortisol, the catecholamines, and glucagon, are largely responsible for these effects. Insulin and growth hormone administration can produce anabolic effects to block the loss of body protein. Administration of specific amino acids, such as glutamine, also appears to be beneficial. However, the hypermetabolic state goes beyond derangement of endocrine hormone levels. Although the cytokines are also important mediators, it is not clear how these mediators, in concert with hormonal changes, produce all of the manifestations of the hypermetabolic state seen in stress.

Stress management: a program designed to facilitate coping.

1. Continual exposure to work-related stressors compounds nurses' workloads, increases their stress levels, and places increased demands on their abilities to adapt. 2. Nurses need to learn and routinely use coping measures to prevent exhaustion and burnout. 3. An in-house stress management program can help nurses learn to cope with constant exposure to work-related stressors, halt the cyclic process of stress, prevent burnout, and decrease turnover.

Valoracion del tratamiento homeopatico en el stress, la impotencia y la eyaculacion precoz / Evaluation of homeopathic treatment in stress, impotence and premature ejaculation

Se estudiaron en una investigacion abierta 60 pacientes del sexo masculino padeciendo stress, impotencia y eyaculacion precoz, cuyas edades fluctuaban entre los 18 y 62 anos (edad promedio 40 anos), de los cuales 34 prestaban servicios en diferentes bancos: 10 se desempenaban como profesionistas 6 eran estudiantes de diversas disciplinas; 5 trabajaban en ocupaciones varias y los 5 restantes, habian pertenecido a instituciones bancarias pero a la sazon estaban jubilados. 50 de dichos casos correspondieron a varones circuncidados, mientras que en 44 individuos existia tabaquismo intenso, moderado y ocasional. 47 sujetos de estudio, bebian mas de una taza de cafe al dia, 47 pacientes consumian diariamente una o mas bebidas gaseosas a base de cola y 37 tomaban una o mas bebidas alcoholicas habitualmente. En 6 casos que cursaban simultaneamente con hipertension, se observo impotencia consecutiva al tratamiento previo clortalidona y metildopa, mientras que la totalidad de los casos tratados (100%), padecian stress en diferentes grados; en 37 se encontro impotencia psiquica (61%), y los otros 23 presentaban eyaculacion precoz (39%). Los 60 pacientes recibieron una dosis diaria de una tableta No.4 de trituracion de Phosphoricum acidum 3D, Glutamicum acidum 3D y Strychninum 3D antes de los alimentos y alternando los medicamentos, durante un lapso que fluctuo entre 15 y 60 dias con excelentes resultados en 49 casos (82%), siendo nulos o poco notables en 11 pacientes (18%). Asimismo todos los casos (100%), fueron tratados exclusivamente por homeopatia y seleccionados, individualizados y repertorizados siguiendo la tecnica homeopatica

Valoracion del tratamiento homeopatico en el stress, la impotencia y la eyaculacion precoz / Evaluation of homeopathic treatment in stress, impotence and premature ejaculation

Se estudiaron en una investigacion abierta 60 pacientes del sexo masculino padeciendo stress, impotencia y eyaculacion precoz, cuyas edades fluctuaban entre los 18 y 62 anos (edad promedio 40 anos), de los cuales 34 prestaban servicios en diferentes bancos: 10 se desempenaban como profesionistas 6 eran estudiantes de diversas disciplinas; 5 trabajaban en ocupaciones varias y los 5 restantes, habian pertenecido a instituciones bancarias pero a la sazon estaban jubilados. 50 de dichos casos correspondieron a varones circuncidados, mientras que en 44 individuos existia tabaquismo intenso, moderado y ocasional. 47 sujetos de estudio, bebian mas de una taza de cafe al dia, 47 pacientes consumian diariamente una o mas bebidas gaseosas a base de cola y 37 tomaban una o mas bebidas alcoholicas habitualmente. En 6 casos que cursaban simultaneamente con hipertension, se observo impotencia consecutiva al tratamiento previo clortalidona y metildopa, mientras que la totalidad de los casos tratados (100 porcento), padecian stress en diferentes grados; en 37 se encontro impotencia psiquica (61 porcento), y los otros 23 presentaban eyaculacion precoz (39 porcento). Los 60 pacientes recibieron una dosis diaria de una tableta No.4 de trituracion de Phosphoricum acidum 3D, Glutamicum acidum 3D y Strychninum 3D antes de los alimentos y alternando los medicamentos, durante un lapso que fluctuo entre 15 y 60 dias con excelentes resultados en 49 casos (82 porcento), siendo nulos o poco notables en 11 pacientes (18 porcento). Asimismo todos los casos (100 porcento), fueron tratados exclusivamente por homeopatia y seleccionados, individualizados y repertorizados siguiendo la tecnica homeopatica

[Differentiated enteral feeding in the post-aggression phase in polytrauma patients. Comparison of a high calorie nutritionally defined diet (whole protein high calorie diet) with a peptide diet]. / Differenzierte enterale Ernährung in der Postaggressionsphase bei Polytraumatisierten. Vergleich einer hochkalorischen nährstoffdefinierten Diät (WPHC-Diät) mit einer Peptid-Diät.

Two groups of 10 patients with an identical mean injury score (25 + 5) were treated from day 3 after injury until day 10 with a whole protein high caloric (WPHC) diet (group A) or with a peptide diet (PD) (group B). Intake of calories, protein, water, Na+ and K+ was measured daily as well as excretion of urine, Na+ and K+. Gastric reflux, bowel movement and plasma levels of Na+ and K+ were registered and the nitrogen balance and Na+/K+ quotient in urine were calculated daily. Clinically both diets were well tolerated, with low gastric reflux and no diarrhea. The calculated caloric demand could be covered in group A on day 7 post-injury (or day 4 of enteral nutrition) and in group B on day 11 post-injury (or day 7 of enteral nutrition). The caloric intake in group A remained significantly higher on days 4-10. There was no difference in nitrogen balance. Total enteral Na+ and fluid intake were significantly lower in group A, but some additional parenteral Na+ had to be given to keep plasma Na+ levels in the normal range. There was no difference in urine output between the 2 groups; therefore, there was a significant fluid retention in group B. Interestingly, the Na+/K+ quotient in urine was significantly higher in group A. The low Na+ intake might influence the back flow of interstitial edema in the 'flow phase'. This diet seems to be adequate, especially for the nutrition of burn patients and of patients with cardiac disease, and can cover the high caloric needs of polytraumatised patients within a few days.